Is Prostate Cancer Hereditary? What You Should Know About Family History and Risk Romeo, November 6, 2024November 6, 2024 Prostate cancer is one of the most common types of cancer in men. If you have a family member, like your father or brother, who has had prostate cancer, you might wonder if that means you could get it too. In this article, we’ll break down what it means for prostate cancer to “run in the family,” the role of genes, and what steps you can take to understand your risk and stay healthy. What Does “Hereditary” Mean? When we say something is “hereditary,” it means it can be passed down from parents to children through genes. Genes are like little instructions in our bodies that decide many things about us, like our hair color or height. Sometimes, genes can also increase the risk of certain diseases, like prostate cancer. Is Prostate Cancer in Your Genes? Not all prostate cancer is genetic, but for some men, their genes can play a part in their chances of getting it. Studies show that around 10-15% of prostate cancer cases are linked to family history. This means that if a close family member, like your father or brother, has had prostate cancer, you may have a higher chance of getting it compared to someone without a family history. Key Genes Linked to Prostate Cancer Certain gene changes, called “mutations,” can make prostate cancer more likely. The most common ones related to prostate cancer are: BRCA1 and BRCA2: You may have heard of these genes because they are also linked to breast and ovarian cancers. Men who have changes in these genes can have a higher risk of prostate cancer. HOXB13: Men with changes in this gene may have a higher risk, especially if they get prostate cancer at a younger age. Does Having a Family History Mean You’ll Get Prostate Cancer? No, having a family history doesn’t mean you will definitely get prostate cancer. It just means your chances might be higher. For example: Close Relatives: If your father or brother had prostate cancer, your risk could be 2-3 times higher. Extended Family: If other family members, like uncles or cousins, had prostate cancer, your risk might still be higher, but not as much as if it were a father or brother. Should You Consider Genetic Testing? If you’re worried about your risk, you might consider genetic testing. Genetic testing looks at certain genes to see if you have changes that might increase your risk of prostate cancer. Testing isn’t for everyone, so it’s often best to talk to a doctor or a genetic counselor to see if it’s a good idea for you. Simple Steps to Lower Your Risk Even if you have a family history, there are things you can do to lower your risk or to catch prostate cancer early if it happens. Here are some tips: Get Regular Check-Ups: Talk to your doctor about when to start getting a blood test called a PSA test. This test can help catch prostate cancer early. Stay Active and Eat Well: A healthy lifestyle can make a big difference. Eating a balanced diet and staying active can help your overall health, including your prostate. Know Your Family History: Tell your doctor about any family members who had prostate cancer. This information can help your doctor decide what tests you might need and when. Final Thoughts Having a family history of prostate cancer can be worrying, but remember that knowing your risk is a good first step. By staying informed, talking with your doctor, and keeping up with regular check-ups, you’re taking control of your health. Knowledge, along with healthy habits, is a powerful tool to help you manage your risk and stay well. Prostate Cancer